Type I diabetes is characterized by the complete destruction of insulin producing cells in the pancreas of the patient, and the complete loss of insulin producing function. When insulin is absolutely deficient in the body...
Atherosclerosis is a chronic inflammatory disease, which is an abnormal reaction of vascular wall to various injuries. It has the characteristics of classic inflammatory degeneration...
Chronic heart failure (CHF) is a common clinical syndrome that occurs when a variety of different harmful factors stimulate enough to cause myocardial dysfunction...
Cardiac hypertrophy is a common pathological process in many cardiovascular diseases. The mechanism of myocardial hypertrophy is very complex, and currently there are many animal models of myocardial hypertrophy targeting different mechanisms...
Hyperlipidemia is a common cardiovascular disease, which is closely related to atherosclerosis and the occurrence and development of cardiovascular and cerebrovascular diseases...
Xenograft transplantation models can be divided into two categories based on the type of transplant: cell line derived xenograft (CDX) and patient derived xenograft (PDX).
This model involves injecting corresponding cells into the corresponding parts of mice, causing in situ tumor growth and later causing tumor metastasis to other parts. This model can be used for cancer related mechanism research and drug development.
More than 90% of cancer patients die due to tumor metastasis and its complications, rather than primary tumors. Tumor metastasis is an important direction in tumor research...
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